Synapses are fundamental building blocks of neural circuits. Synapse formation requires complex regulation involving cell adhesion molecules, secreted molecules, transcription factors and so forth.

The differential regulation of neuronal signal strength in pre- and postsynaptic cells contributes to information processing in the brain ...

Synaptic transmission is the biological process by which a neuron communicates with a target cell across a synapse. Chemical synaptic transmission involves the release of a neurotransmitter from the ...

Recent technological advances facilitate the reconstruction of complete brain connectomes in small organisms and partial connectomes in mammals, involving the mapping of the network of neurons and ...

Synthetic Trogocytosis (SynTrogo) enables the "nibbling" of neuronal membranes by astrocytes through engineered ligand and receptor proteins. Upon SynTrogo induction, the synaptic density of the ...

Identifying the connections for all the neurons in the brain has perplexed researchers for decades. A solution may soon be at hand, as improved molecular probes and high throughput assays for neurons ...

Alzheimer's disease (AD) is a debilitating neurodegenerative condition that affects a significant proportion of older people worldwide. Synapses are points of communication between neural cells that ...