Breast cancer development is not solely the result of cancer cells acting independently, it involves a dynamic and complex ecosystem composed of cancer cells, immune cells, fibroblasts, adipocytes, ...

Preclinical data demonstrate enhanced efficacy of PLT012 in pMMR colorectal cancer models - Findings position CD36 as a promising metabolic checkpoint target in an underserved patient population DOVER ...

Head and neck cancer remains a major global health challenge, ranking among the six most common cancers worldwide and claiming hundreds of thousands of lives each year. A growing body of evidence now ...

St. Jude Children's Research Hospital scientists have discovered how tumors disable immune "gatekeeper" cells that alert the ...

A metabolic enzyme found in the support cells surrounding tumors may hold the key to predicting which cancer patients will ...

Tumor growth unfolds within a tumor microenvironment (TME) defined by metabolic–immune crosstalk. Emerging evidence indicates that cancer cells not only reprogram glycolysis but also alter amino acid, ...

In this study, a principle of cancer cell metabolism was elucidated by integrating 13 C-metabolic flux analysis with flux balance analysis. The findings reveal that glycolysis-dependent, less ...

A research team led by Purdue University's W. Andy Tao has discovered a new type of protein modification related to cellular ...

Up to 80 percent of patients with cancer struggle with cachexia, often called wasting syndrome, which is a condition characterized by the inability to gain or maintain body weight. One of the reasons ...

Pilatus Biosciences to Present New Data Highlighting Sex-Specific Efficacy of CD36-Targeting Antibody in Colorectal Cancer at ...