For the roughly 30,000 Americans living with hemophilia and thousands more with rare enzyme deficiencies, treatment often ...

CAR T cells are patient-derived, genetically engineered immune cells. They are "living drugs" and constitute a milestone in modern medicine. Equipping T cells, a key cell type of the immune system, ...

Researchers at Pohang University of Science and Technology (POSTECH) have built a platform that steers cell behavior using synthetic DNA produced inside cells, without making a single permanent change ...

The immune system already knows how to fight cancer. The problem has always been that it runs out of fuel too quickly. A team ...

Researchers in the lab of Hans-Peter Kiem, MD, PhD, at Fred Hutch Cancer Center have devised a method that could one day treat genetic hematologic disorders by correcting how the body makes blood ...

The evolution of biomedical science can be appreciated through studies of hemoglobin, the oxygen-carrying protein in red cells. Before molecular cloning, the geneticist Arno Motulsky noted, “Many ...

A new gene-editing technique enables the correction of multiple genetic mutations simultaneously, transforming the prospects for millions living with complex inherited diseases, such as cystic ...

"RNA modifications are central to how cells respond to their environment," said Gudrun Stengel, Ph.D., Chief Executive Officer of Alida Biosciences. "With EpiPlex Tri-Mod, we move beyond method ...

Detecting whether osteosarcoma, a rare but aggressive bone cancer that most often affects children and adolescents, has ...

Directly transferring healthy mitochondria or cytoplasmic components into target cells is particularly relevant for regenerative medicine.