C3 glomerulopathy (C3G) and primary immune complex membranoproliferative glomerulonephritis (IC-MPGN) are two rare kidney diseases. They’re both driven by activity of the complement system, which is a ...

C3G and IC-MPGN both cause protein deposits that reduce kidney function. Overactive proteins in the immune system lead to these different conditions. C3G and IC-MPGN are rare kidney conditions. They ...

Current treatment methods for C3 glomerulopathy (C3G) help support kidney function and suppress immune system activity. Emerging therapies interrupt the proteins responsible for disease activity. C3G ...

Objective SLE is a systemic autoimmune disease in which the complement system plays a key pathogenic role, yet the ...

Proteomics is the large-scale study of proteins, particularly their structures and functions. It involves the systematic identification, quantification, and analysis of the entire protein complement ...