In a study published in Nature Methods, a research group developed a highly sensitive proteomics method called peptide-centric local stability assay (PELSA), which enables the simultaneous ...
Macromolecular CSPs can report on conformational averaging between free and bound states, and so can be used to extract binding constants for (weakly binding) ligands, as shown in Figure 2B. The ...
In a study published in Nature Methods, a research group led by Prof. YE Mingliang from the Dalian Institute of Chemical Physics of the Chinese Academy of Sciences (CAS), collaborating with Prof. LUO ...
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