Neurofibrillary tangles mark Alzheimer’s disease and a plethora of primary tauopathies. How best to study them in the lab? Most mouse tauopathy models overexpress the human tau protein and are highly ...

Hidden inside every organ, microscopic fibers form a scaffolding that quietly shapes how we move, think, and heal. For the first time, scientists have produced detailed maps of these fiber webs across ...

In this Innovation Spotlight, Treutlein shares her excitement of using organoids to model the human brain, harnessing AI to accelerate laboratory discoveries, and discusses how massive-scale ...

Researchers with the global Human Cell Atlas (HCA) consortium report significant progress in their quest for a better understanding of the cells of the human body in health and disease, with the ...

Looking ahead: Every year, tens of thousands of Americans receive organ transplants, yet demand still outstrips supply. Now, a research team at Carnegie Mellon University believes the way out of that ...

Researchers are no longer just simulating brains in silicon, they are wiring living human neurons into machines and asking them to compute. Tiny clusters of brain cells, grown from stem cells and ...

The visible effects of ageing on our body are in part linked to invisible changes in gene activity. The epigenetic process of DNA methylation — the addition or removal of tags called methyl groups — ...