A team of scientists at the MRC Laboratory of Medical Sciences (LMS) has uncovered a previously unknown mechanism that controls how genes are switched ‘on’ and ‘off’ during embryonic development.

Gene regulation timing, controlled by non-coding DNA elements, drives limb development, with disruptions leading to distinct ...

Transposable elements are stretches of DNA that can move around the genome. Many of these DNA sequences originate from long ago, when viruses inserted their genetic material into our ancestors' ...

All cells contain the same DNA but must turn specific genes ‘on’ and ‘off’ – a process known as gene expression – to create different body parts. The cells in your eyes and arms harbour the same genes ...

Researchers have gained new insights into the mechanism behind the spatial organization of DNA within the cells of early embryos. When an embryo is first formed after fertilization, each cell has the ...

For the first time, a stem cell model has produced a structure resembling an early human embryo with a yolk-sac-like ...

In a new study published in Genes & Development, research led by Dr. Lila Allou at the MRC Laboratory of Medical Sciences (LMS) in London and Professor Stefan Mundlos at the Max Planck Institute for ...

IQ is about 50% genetic, but it’s one of over 2,000 factors considered in genetic assessments. Selecting embryos involves ...

A small tissue fold in fly embryos, once thought purposeless, plays a vital role in stabilizing tissues. Researchers show that it absorbs stress during early development, and its position and timing ...

By examining genetic clues that linger in adult cells, scientists have now gained surprising insights into the developmental ...