In blood cancers such as chronic lymphocytic leukemia, B cells of the immune system multiply uncontrollably. One form of therapy involves labeling the CD20 protein on the surface of the B cells with ...

Chemists discover how key contrast agent works, paving a way to create new markers needed for correlative microscopy that can image the structure and signaling of cells at the same time. Two labs at ...

Electron microscopy is a powerful technique that provides high-resolution images by focusing a beam of electrons to reveal fine structural details in biological and material specimens. 2 Because ...

Evanescent scattering microscopy is a label-free optical imaging technology that uses evanescent fields and interferometric light scattering to detect and characterize single biomolecules in real time ...

In 2005, few neuroscientists would have bet that electron microscopy could map entire neural circuits in three dimensions. The technique was slow and cumbersome, offering only thin slices of brain ...

Confocal microscopy is a specialized fluorescence imaging technique that scientists use to acquire images at greater resolution than conventional microscopy. 1 In addition to scanning the lateral x ...

Photo-induced force microscopy began as a concept in the mind of Kumar Wickramasinghe when he was employed by IBM in the early years of the new millennium. After he came to the University of ...

Scientists have developed a new imaging technique that uses a novel contrast mechanism in bioimaging to merge the strengths of two powerful microscopy methods, allowing researchers to see both the ...

In a study published in ACS Nano, researchers from National Taiwan University report a new expansion microscopy strategy termed high-fold homogeneous expansion microscopy (hiHomoExM), capable of ...

Using light to measure ever-smaller objects has been central to progress in many scientific disciplines for centuries. As far back as 1873, German physicist Ernst Abbe proved that light diffraction ...

Two labs at the University of Utah’s Department of Chemistry joined forces to improve imaging tools that may soon enable scientists to better observe signaling in functioning cells and other molecular ...