For decades, the central dogma of molecular biology—DNA makes RNA, RNA makes protein, protein makes phenotype—was the guiding framework for understanding inheritance and disease. This model explained ...

The enzyme RNA polymerase (RNAP) carries out transcription, copying DNA into RNA. It's the first step in gene expression, and ...

Our genes contain all the instructions our body needs to function, but their expression must be finely regulated to guarantee that each cell performs its role optimally. This is where DNA and RNA ...

A new method developed at Baylor College of Medicine and collaborating institutions allows researchers to better understand how RNA works. The method is a powerful strategy for identifying intricate ...

Multiple forms of double-stranded RNA (blue, magenta, orange structures) cross cell membranes with the help of a conserved protein located in novel sites (colored by depth) throughout the roundworm's ...

BUFFALO, N.Y. — Look inside a brain cell with Huntington’s disease or ALS and you are likely to find RNA clumped together. These solid-like clusters, thought to be irreversible, can act as sponges ...

Fred Hutch researchers invent a CRISPR screening method to understand RNA-binding proteins often mutated in cancer and other diseases In biology’s standard tale of two acids — deoxyribonucleic (DNA) ...

All starting from the same DNA, neurons ultimately take on individual characteristics in the brain and body. Differences in which genes they transcribe into RNA help determine which type of neuron ...

Researchers from Children's Hospital of Philadelphia (CHOP) developed a new RNA sequencing strategy that can reveal how genetic variants disrupt gene function and improve the diagnosis of rare ...