Intestinal tuft cells divide to make new cells when immunological cues trigger them. Additionally, in contrast to progenitor- and stem cells, tuft cells can survive severe injury such as irradiation ...

Tuft cells are present throughout the intestinal tract as well as in many organs. Studies in mice have shown that when tuft cells sense the presence of pathogens, they signal to immune cells and to ...

In a breakthrough for the advanced study of gut health, scientists have developed a 3D microscopic version of the human intestines condensed into a small chip about half the size of a five-cent coin.

Thanks to lab-grown miniature intestines, researchers at Uppsala University have successfully mapped how aggressive Shigella bacteria infect the human gut. The study opens the door to using cultured ...

Research from an international team finds that the human gut is a site of rapid change, with recent and important deviations from other mammals, including our closest living relative, the chimpanzee.

While in vivo animal models are commonly employed for pharmacokinetic studies, they are often expensive, low in throughpu,t and typically fail to accurately replicate key characteristics of the human ...

Organ-Chips as a Platform for Studying Effects of Space on Human Enteric Physiology (Gut on Chip) examines the effect of microgravity and other space-related stress factors on biotechnology company ...

Researchers have discovered a way to help aging intestines heal themselves using CAR T-cell therapy. By targeting senescent cells that build up over time, the treatment boosted gut regeneration, ...

Intestinal tuft cells divide to make new cells when immunological cues trigger them. Additionally, in contrast to progenitor- and stem cells, tuft cells can survive severe injury such as irradiation ...

Prof LIM Chwee Teck (seated), together with Dr Nishanth Venugopal MENON (right) and Dr LEE Jee Yeon (left), from the National University of Singapore, jointly developed the new ‘gut-on-chip’ platform.