Everyday DNA mutations can help us understand immune function and aging—and even mitigate harm caused by some inherited ...

(TP53), widely known as the “guardian of the genome,” is one of the most frequently altered genes in human cancer. While its canonical tumor-suppressive ...

While most known types of DNA damage are fixed by our cells’ in-house DNA repair mechanisms, some forms of DNA damage evade repair and can persist for many years, new research shows. This means that ...

A new microfluidic chip simplifies detecting and quantifying DNA by analyzing electrical impedance signals that vary based on DNA flowing across a biosensor inside the chip. The proof-of-concept ...

Genes are short sections of DNA that determine an animal’s traits—everything from coat color and claw strength to body shape and health. But sometimes, these genes mutate. And while the word itself ...

Researchers have refined a powerful DNA sequencing tool that can uncover hidden mutations that occur naturally in our bodies as we age. In the largest study to date, they have used the tool to provide ...

Scientists have identified a genetic mutation in a gene called SHLP2, which encodes for a microprotein in mitochondria, and can reduce a carrier's likelihood of developing Parkinson's disease by 50 ...

Characteristics of Clonal Hematopoiesis (CH) Mutations - a) We identified somatic mutations in known clonal hematopoiesis of indeterminate potential (CHIP) driver genes using peripheral blood ...

Scientists have discovered a surprising mechanism by which the inherited genetic mutation known to cause Huntington's disease leads to the death of brain cells. The findings change the understanding ...

A man sits outside and holds a slim menthol cigarette between his fingers. Close-up with focus on the cigarette. The study provided a comprehensive examination of how lifestyle and environmental ...