DNA/RNA-based next-generation sequencing allows earlier diagnosis of neoplastic bile duct strictures, a prospective multicenter real-time study finds.

This eBook explores next-generation sequencing (NGS) methods and their applications in neurological and cancer research, with key content from BioTechniques’ digital hub and Taylor & Francis journals, ...

Whole genome analysis plays a critical role in the development of life-saving diagnostics, therapeutics, and vaccines, with growing interest in noncoding regions and Whole genome analysis plays a ...

This study demonstrates that NGS-MSI is noninferior to IHC-MMR and can identify MSI-H tumors that IHC-MMR is unable to detect and conversely IHC-MMR can identify MMRd tumors that NGS-MSI misses. This ...

Nearly half of people diagnosed with advanced cancer over a recent 5-year period did not undergo next-generation sequencing, according to results of a retrospective cohort study.Rates improved over ...

Real-World Plasma Thymidine Kinase Activity in High-Risk and Metastatic Hormone Receptor–Positive, Human Epidermal Growth Factor Receptor 2–Negative Breast Cancer Treated With Cyclin-Dependent Kinase ...

In the largest study of its kind, the diagnostic yield of mNGS was greater than conventional test methods mNGS alone identified 34% more pathogens than all direct-detection methods combined 72% of ...