The ability to alter protein binding can create tailored therapeutics with reduced side effects, sensitive diagnostic tools, targeted drug delivery and sustainable bioremediation. BIRMINGHAM, Ala. – ...
In a study published in Nature Methods, a research group developed a highly sensitive proteomics method called peptide-centric local stability assay (PELSA), which enables the simultaneous ...
Swedish chemist Jöns Jacob Berzelius, in a letter to a fellow chemist, first suggested the name ‘proteins’ for a particular class of biological substances, deriving it from the Greek word proteios, ...
The ability to alter proteins to refine control over binding affinity and specificity can create tailored therapeutics with reduced side effects, highly sensitive diagnostic tools, efficient ...
Various approaches to such protein redesign have drawbacks. Traditional methods include time-consuming trial and error efforts, and many models in the emerging field ...
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