The answer depends on the questions you’re trying to answer, as well as the origin, quantity, and quality of your samples. In this article, we’ll briefly discuss several RNA-seq workflows, how they ...

In this Teach Me in 10 episode, Dr. Shaveta Goyal, Group Leader of NGS at Takara Bio USA, outlines the practical considerations that matter most when selecting an RNA-seq workflow.<br /><br /> ...

RNA plays critical roles in nearly all biological processes, but current methods for sequencing RNA are significantly limited. This is partially because RNA molecules are chemically modified within ...

Years of experiments and databases filled with RNA-seq results belie the simple reality that, until fairly recently, it was impossible to analyze RNA directly. The RNA-seq studies performed with ...

By tagging neurons with molecular "barcodes," researchers have mapped connections among thousands of neurons in the mouse brain with unprecedented speed and resolution. The approach could expand ...

Inside every cell, thousands of molecular signals collide, overlap, and compensate, obscuring the true drivers of gene expression. Scientists have now developed a way to silence that cellular noise, ...

Researchers at Karolinska Institutet have developed a rapid and cost-efficient sequencing method that can identify antibiotic ...

Genome editing using CRISPR/Cas9 "gene scissors" is a powerful tool for biological discovery and for identifying novel drug targets. In pooled CRISPR screens, a large number of cells are edited ...

EMBL researchers created SDR-seq, a next-generation tool that decodes both DNA and RNA from the same cell. It finally opens access to non-coding regions, where most disease-associated genetic variants ...