CAR T-cell therapy is an immune-reprogramming procedure that turns a patient's own immune cells into cancer-fighting ...

Researchers at Oregon Health & Science University have uncovered a key reason why immunotherapy has largely failed in pancreatic cancer—and identified a promising strategy to overcome that resistance.

In order to reprogram readily available cells into specific immune cells that fight various diseases, one must know the "recipe" for the transformation. Researchers at Lund University have now created ...

Leuven, 11 March 2025 – Solid tumors often provide a challenging environment for the T cells of our immune system. By reprogramming the metabolism of T cells, scientists at the VIB-KU Leuven Center ...

Solid tumors often provide a challenging environment for the T cells of our immune system. By reprogramming the metabolism of T cells, scientists at the VIB-KU Leuven Center for Cancer Biology and ...

Cancer cells can create an antioxidant-rich environment that deprives tumor-fighting T cells of reactive oxygen species, or ROS, which those immune cells need for normal activation and signaling. The ...

A man who was fully paralyzed is now able to stand after receiving an injection of reprogrammed stem cells into his injured spinal cord. The result, announced by researchers in Japan, marks a rare and ...

In order to reprogram readily available cells into specific immune cells that fight various diseases, one must know the "recipe" for the transformation. Researchers at Lund University have now created ...

For the first time, specialised cells have been reprogrammed into the equivalent of embryonic stem cells without using genes that might trigger cancer. The new method, which places the proteins ...