Cell signaling is crucial for cells to communicate and function correctly. Disruptions in these pathways, caused by genetic mutations or environmental factors, can lead to uncontrolled cell growth, ...

A new review brings attention to the STING pathway as a critical regulator in both colitis and colon cancer, highlighting its complex and often opposing roles in inflammation and tumor development.

For most children diagnosed with medulloblastoma, the most common malignant pediatric brain tumor, survival rates are encouraging. But for a subset, remission is not the end of the story. Roughly 30% ...

A new study leverages a modified pyrvinium hybrid to block GLI and WNT pathways, halting pediatric medulloblastoma relapse.

Researchers discovered that disrupted PTH1R signaling drives abnormal cementum growth and tooth-bone fusion in adult ...

Chronological aging is a major risk factor for many neurodegenerative disorders affecting both the brain and the eye, including Alzheimer’s disease, ...