Dysregulation of mRNA translation is a frequent feature of neoplasia. As the components of the translation machinery integrate almost all oncogenic signals, targeting the protein synthesis machinery ...

Cancer is the Houdini of diseases because it escapes elaborately contrived predicaments. Like Houdini, who was known to emerge triumphant after being handcuffed, locked in a trunk, and tossed into a ...

Researchers have shown that translation of the genetic information stored in our DNA is much more complex than previously thought. This discovery was made by developing a type of advanced microscopy ...

The functions of the individual complexes have been well understood for many years. Ribosomes, often referred to as the cell’s protein factories, translate messenger RNA (mRNA) into a specific ...

Efficacy of ocaratuzumab (AME-133v) in relapsed follicular lymphoma patients refractory to prior rituximab. Use of the cumulative amount of serum-free light chains (sFLC) at diagnosis and PET2 for the ...

Each cell in our body contains the same DNA, yet different cells, like brain cells or muscle cells, have different functions. The differences in cell function depend on which parts of the genetic ...