The non-coding genome, once dismissed as "junk DNA", is now recognized as a fundamental regulator of gene expression and a key player in understanding complex diseases. Following the landmark ...

The human genome contains about 20,000 protein-coding genes, but that only accounts for roughly two percent of the genome. For many years, it was easier for scientists to simply ignore all of that ...

Nearly 25 years after scientists completed a draft human genome sequence, many of its 3.1 billion letters remain a puzzle. The 98% of the genome that is not made of protein-coding genes — but which ...

"With up to half of individuals with rare diseases currently living without a diagnosis, exploring the non-coding DNA can provide answers for families with rare conditions." The researchers found that ...

Researchers have revealed that so-called ‘junk DNA’ contains powerful switches that help control brain cells linked to Alzheimer’s disease. When people picture DNA, they often imagine a set of genes ...

Scientists have found new genetic causes for diabetes in babies – in a part of the genome that has historically been overlooked in genetic studies. Until recently, most research has investigated ...

Almost 1,500 genes have been implicated in intellectual disabilities; yet for most people with such disabilities, genetic causes remain unknown. Perhaps this is in part because geneticists have been ...

Researchers have pinpointed a long non-coding gene that plays a distinct role in the social and stereotypic repetitive ...

Long Noncoding RNAs (LncRNAs) are proven to be critical in cancer biology playing a significant role in tumor formation and ...

A new study identifies PTCHD1-AS as a key non-coding gene that shapes social and repetitive behaviors in autism without affecting cognition.