Researchers found that mice lacking membrane ERα signaling in osteoblast lineage cells had significantly lower cortical bone mass, highlighting the pathway’s critical role in maintaining the strength ...

Researchers reveal how bone marrow fat reprograms immune signaling to promote osteoclast activity and weaken bones ...

Obesity alters bone health not only through increased body weight but also by reshaping the bone marrow environment.

Estrogen plays an important role in keeping bones healthy. Now, researchers investigated how membrane-initiated estrogen receptor alpha (mERα) signaling in specific cell types of female mice affects ...