Scientists have gained tremendous control over the genome with CRISPR editing systems, that use a guide RNA molecule to ...

The Tas protein uses an RNA guide to recognize a specific target DNA sequence. A vast search of natural diversity has led scientists at MIT’s McGovern Institute and the Broad Institute of MIT and ...

Now, following up on that success, a large Chinese collaboration has followed up with a description of an improved gene ...

Researchers have built a series of CRISPR-based platforms that can switch endogenous genes on and, just as critically, dial the activation level up or down by adjusting a small-molecule dose. The work ...

DNA is transcribed into RNA, which is then translated into proteins. This is the central dogma of molecular biology – a mantra taught to every biology undergraduate student to be recalled and expanded ...

CRISPR functions as a programmable genetic memory system derived from bacterial immune defenses against viral infections. Guide RNA allows for rapid multiplexed targeting compared to older ...

ORNL scientists created a biosensor technology that lets researchers visualize and track RNA activity in living plants, using a molecular splicing technique and a fluorescent marker protein. *This ...

In modern functional genomics, understanding how specific genes control cellular behavior requires both targeted intervention and high-resolution analysis. That’s where Perturb-Seq comes in—a method ...

Cells in our bodies produce RNA based on genetic information stored in DNA, and RNA serves as a blueprint for making proteins. Researchers at KAIST have discovered a new phenomenon: Removing "circular ...

SANTA CRUZ — A Ph.D. graduate student in biomolecular engineering at UC Santa Cruz, with a background in computer science and mathematics, has created an innovative software program called CRISPRware, ...