Genome assemblies from 65 individuals, representing a variety of the world’s populations, are advancing the scientific exploration of complex genetic structural variation. Structural variations are ...

The work demonstrates the power of ancient DNA to illuminate human biology and medicine in addition to history. A massive ...

Scientists have discovered that a gene called MUC19, inherited from Denisovans through ancient interbreeding, may have played a vital role in helping Indigenous ancestors adapt as they migrated into ...

The most complex engineering of human cell lines ever has been achieved by scientists, revealing that our genomes are more resilient to significant structural changes than was previously thought. The ...

Structural variants (SVs) are alterations in the DNA sequence that involve large-scale changes, typically longer than 50 base pairs. Advances in long-read sequencing have significantly increased ...

Researchers have significantly expanded the catalogue of known human genetic variation. The resulting datasets, shared in two back-to-back publications in the journal Nature, constitute what may be ...

Among genetically identical "agouti viable yellow" (A vy) mice, some are brown and lean while others are yellow and obese. These differences are due to epigenetics, a system of molecular tags—such as ...

Ribosomal RNA (rRNA), made from many copies of ribosomal DNA (rDNA), is the core component that powers ...

Our species is the last living member of the human family tree. But just 40,000 years ago, Neanderthals walked the Earth, and hundreds of thousands of years before then, our ancestors overlapped with ...