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Blood Cells That Look Like Targets 🎯🩸🔬 Red blood cells that look like targets, are called “Target Cells,” and are scientifically named “Codocytes.” Target cells are red blood cells with an increased cell membrane-to-volume ratio due to either gain of membrane lipids, or to a reduction in cell volume. You may see target sells in thalassemias, hemoglobinopathies, obstructive, jaundice, asplenia, and hereditary deficiency lecithin-cholesterol acts transferase (LCAT). Target cells may also be see
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1. Target Cells Also called: Codocytes Appearance Look like a bull’s-eye / shooting target Dark center, surrounded by a clear ring, then a dark outer rim Thin RBC with increased surface area Why do they form? Excess cell membrane compared to hemoglobin Reduced hemoglobin content or altered lipid composition Seen in Thalassemia (very common) Liver disease Iron deficiency anemia Hemoglobinopathies (HbC, HbS) Post-splenectomy Lab & Exam Points ⭐ Common in microcytic anemias Often increased after sp
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