Complement System Made Easy- Immunology- Classical Alternate & Lectin pathway
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Code HAVIC @medschoolbro = Mystery Discount Complement System: 30-sec Review 🛣 Three pathways lead to complement activation: • Classical pathway activated by IgG or IgM • Alternative pathway activated by microbial surfaces • Lectin pathway activated by mannose on microbes 🌀 C3 convertase produces C3a and C3b. 🔥 C5 convertase produces C5a and C5b. 💥 MAC (C5b–C9) forms pores that destroy microbes, especially Neisseria. 🔑 Key functions: • C3a and C5a trigger mast cell degranulation • C5a direc
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The complement system doesn't generate compliments for you... but it does help destroy pathogens in your body! Learn all about it in today's #ClinicalCuts. The complement system refers to a group of plasma proteins called the complement proteins, which are produced in the liver, and act collectively to help destroy pathogens. Think of them like a little militia that “complement” the work of antibodies. There are actually three complement pathways: • The classical pathway: called that because it
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