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Nakakasira ba talaga ng kidney ang metformin? 💊 Hindi nephrotoxic ang metformin—pero bakit kailangan pa ring bantayan ang kidney function? Paliwanag natin. 👩‍⚕️ #Metformin #KidneyHealth #Diabetes #DiabetesPH #DocMomDiaries
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For over 60 years, we thought metformin worked mainly through the liver and gut. But new research suggests the brain may play a major role too. This study identified a specific brain pathway (Rap1 in the hypothalamus) that appears critical to metformin’s glucose-lowering effects, potentially reshaping how we understand one of the world’s most prescribed diabetes medications. Source: Sci. Adv. 2025;11:eadu3700
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